Nebraska vs. Colorado odds, spread, time: 2024 college football picks, Week 2 predictions by proven model

One of the most watched college football games of the 2023 season was Colorado vs. Nebraska in early September. The Buffs won that matchup 36-14 behind a strong performance from quarterback Shedeur Sanders. Head coach Deion Sanders looks to make it four straight wins for the Buffaloes over their longtime rivals when CU travels to Memorial Stadium in Lincoln on Saturday to take on the Huskers. The Buffs won their season opener, defeating North Dakota State 31-26. Travis Hunter put forth a Heisman Trophy caliber performance in the win. Nebraska also won its season opener, dominating UTEP en route to a 40-7 victory. Highly-regarded freshman Dyland Raiola was sharp in his first collegiate start under head coach Matt Rhule.

Kickoff is at 7:30 p.m. ET. The Huskers are 6.5-point favorites in the latest Colorado vs. Nebraska odds, per SportsLine consensus. The over/under for total points is 55.5. Before entering any Colorado vs. Nebraska picks, you’ll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of over $2,000 for $100 players on its top-rated college football picks against the spread. It is also coming off a profitable 13-9 season on top-rated spread picks. Anyone who has followed it has seen strong returns.

The model has set its sights on Colorado vs. Nebraska. You can head to SportsLine to see its picks. Here are several college football betting lines for the Nebraska vs. Colorado game:

• Nebraska vs. Colorado spread: Nebraska -6.5
• Nebraska vs. Colorado over/under: 55.5 points
• Nebraska vs. Colorado money line: Nebraska -243, Colorado +196
• Nebraska vs. Colorado picks: See picks here

Why Nebraska can cover

Nebraska is coming off a strong start to the season, cruising to a 40-7 win over UTEP in its first game with star freshman quarterback Dylan Raiola. He completed 19 of 27 passes for 238 yards and two touchdowns, with senior wide receiver Isaiah Neyor accounting for 121 yards and one score. Raiola was recognized as the Big Ten Freshman of the Week following that performance. 

Sophomore running back Emmett Johnson paced a balanced rushing attack with 71 yards on eight carries, as the team finished with 223 rushing yards. The 40 points scored were the most by a Nebraska team since 2021 and helped them win an opener for the first time in five years. Colorado is just 2-15 in its last 17 road games, and it lost six straight games down the stretch last season. See which team to pick here. 

Why Colorado can cover

The Buffs have arguably the best player in college football in Travis Hunter. The two-way star has the talent and potential to be an early NFL Draft pick at both cornerback and wide receiver. He was outstanding against North Dakota State, catching seven passes for 132 yards and three touchdowns, and notching three solo tackles from his cornerback position on defense.

Senior Shedeur Sanders made a strong case for consideration as the top quarterback in the country in his Week 1 performance against NDSU. He completed 26 of 34 passes for 445 yards, four touchdowns, and one interception in the win. For the Buffs to have a chance at pulling off the road upset, Sanders will have to be at the top of his game. See which team to pick here. 

How to make Nebraska vs. Colorado picks

The model has simulated Colorado vs. Nebraska 10,000 times and the results are in. The model is leaning Under, projecting 51 combined points. It’s also generated a point-spread pick that is hitting in more than 60% of simulations. You can only see the pick at SportsLine.

So who wins Nebraska vs. Colorado, and which side of the spread is hitting more than 60% of the time? Visit SportsLine now to see which side of the Colorado vs. Nebraska spread to jump on, all from the advanced computer model that’s up over $2,000 on its top-rated college football spread picks since its inception, and find out.