Colorado vs. Nebraska prediction, odds, time: 2024 college football expert picks, expert Deion Sanders bets

A bitter college football rivalry is on tap for Saturday, with Deion Sanders and the Colorado Buffaloes (1-0) set to take on the Nebraska Cornhuskers (1-0) at Memorial Stadium in Lincoln. The Buffs are coming off a 31-26 win over North Dakota State in their season opener. Heisman Trophy candidates Shedeur Sanders (445 yards, four touchdown passes) and Travis Hunter (132 yards, three touchdowns) excelled in the win. The Huskers opened their season with a dominant 40-7 win over UTEP. Heralded freshman quarterback Dylan Raiola threw for 238 yards and two touchdowns in his college debut. 

Kickoff is at 7:30 p.m. ET from Memorial Stadium in Lincoln, Nebraska. The Huskers are 7.5-point favorites in the latest Colorado vs. Nebraska odds, per SportsLine consensus. The over/under for total points is 56.5. Before making any Colorado vs. Nebraska picks, you need to see the Week 1 college football predictions and betting advice from SportsLine’s Jimmie Kaylor. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season way up.

Now, Kaylor has dialed in on Colorado vs. Nebraska on Saturday and just revealed his picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and college football betting lines on the spread, money line, and over/under for Nebraska vs. Colorado:

• Colorado vs. Nebraska spread: Nebraska -7.5
• Colorado vs. Nebraska over/under: 56.5 points 
• Colorado vs. Nebraska money line: Nebraska -277, Colorado +233
• Colorado vs. Nebraska picks: See picks at SportsLine

Why Colorado can cover

Colorado has an immense amount of speed and explosiveness on the offensive side of the ball. Senior Shedeur Sanders is one of the top quarterbacks in the country, and he looked comfortable in Pat Shurmur’s system in Week 1. Wide receivers Travis Hunter, Jimmy Horn Jr., Will Sheppard, and LaJohntay Wester will put constant pressure on Nebraska’s secondary, and all are capable of scoring every time they touch the ball. 

Hunter is a dominant player who can impact the game on both sides of the ball. As a receiver, Hunter has game-breaking speed, and is outstanding in the red zone. As a defensive back, the former five-star recruit is a true lockdown cornerback who excels in man and zone coverage schemes. Nebraska will have to commit to knowing where Hunter is at on the field at all times. See which team to pick here.

Why Nebraska can cover

Nebraska has a noticeable advantage on the line of scrimmage in this matchup. Colorado has an all-new starting offensive line, and the Huskers have experience in their defensive front seven. If Nebraska can get a consistent pass rush on Sanders, it can help neutralize Colorado’s speed at the wide receiver position. 

Colorado’s defense struggled mightily for most of the game against North Dakota State. Nebraska rushed for 223 yards against UTEP, and the Buffs had issues stopping the run in their season opener. Freshman quarterback Dylan Raiola looked poised in his first collegiate start and his throwing ability will put a lot of pressure on Colorado’s secondary. See which team to pick here.

How to make Nebraska vs. Colorado picks

Kaylor has analyzed Colorado vs. Nebraska from every angle and he’s leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He’s only sharing what it is, and which side to back, at SportsLine.

So who wins Colorado vs. Nebraska on Saturday in Lincoln, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who profited $5,790 for $100 college football bettors in 2023, and find out.